What is a biomarker?

A biomarker is intended to function as a surrogate endpoint. A surrogate endpoint is intended to substitute for a clinical endpoint. A clinical endpoint is a characteristic or variable that reflects how a patient feels, functions, or survives.

The word surrogate actually comes from the latin word subrogare, which means to substitute.

So, a biomarker is a characteristic that is objectively measured and evaluated as an indication of normal biologic processes, pathogenic processes, or pharmacologic responses to a therapeutic intervention. A biomarker is an objective indications of medical state observed from outside the patient.

Also, a…

Christian Baghai

Consultant clinical statistical programmer

Get the Medium app

A button that says 'Download on the App Store', and if clicked it will lead you to the iOS App store
A button that says 'Get it on, Google Play', and if clicked it will lead you to the Google Play store