What is a biomarker?

A biomarker is intended to function as a surrogate endpoint. A surrogate endpoint is intended to substitute for a clinical endpoint. A clinical endpoint is a characteristic or variable that reflects how a patient feels, functions, or survives.

The word surrogate actually comes from the latin word subrogare, which means to substitute.

So, a biomarker is a characteristic that is objectively measured and evaluated as an indication of normal biologic processes, pathogenic processes, or pharmacologic responses to a therapeutic intervention. A biomarker is an objective indications of medical state observed from outside the patient.

Also, a…










Christian Baghai

Consultant clinical statistical programmer

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