Sodium is an essential mineral that our bodies need to maintain a healthy balance of water and minerals. However, like most things in life, too much of a good thing can be harmful. …

Have you ever wondered what makes your heart beat or your muscles move? The answer lies in the power of two vital elements: sodium and potassium. These two elements work together in a delicate balance to act like a chemical battery that powers our nerve impulses and muscle contractions. The…

Thanksgiving is a time of year when families gather together to give thanks for the good things in their lives. One of the most important aspects of this holiday is the feast that is prepared. From roasted turkey to creamy mashed potatoes, the delicious dishes that are served are the…

Introduction: Clinical laboratory data plays a crucial role in determining the safety and efficacy of new pharmaceutical agents during clinical trials. This data is typically handled by two types of labs: central labs and local labs. …

Introduction: Laboratory tests are essential for assessing the safety and efficacy of new pharmaceutical agents in human clinical trials. In this article, we will focus on the specific laboratory tests commonly used in hematology, blood chemistry, urinalysis, coagulation, and functional testing. Hematology: Hematology tests are used to evaluate the cellular…

Introduction: Laboratory tests are an essential part of clinical trials in drug development, providing valuable information about the safety and efficacy of new pharmaceutical agents. …

Introduction: Blood is a vital fluid that circulates throughout the body, delivering oxygen and nutrients to organs and tissues while removing waste products. The composition of blood includes both cellular components and plasma, a fluid containing various proteins and nutrients. …

Introduction: Clinical trials are an essential part of the drug development process, and the safety and efficacy of a new pharmaceutical agent are evaluated through a variety of methods, including clinical laboratory data. Clinical laboratory data is a crucial component of the safety profile for any drug under study. …

Blinded or confirmatory open label trials are essential in gathering evidence on the efficacy and safety of new drugs or treatments. However, maintaining blinding during interim analyses can be challenging, particularly when independent analyses through regular DMC are required. In such trials, rules should be defined, such as SOPs and…